• Product NameRecombinant human TGFb2
• Host SpeciesHEK293
• Purification> 95% by Tris-Bis
• Endotoxin< 3 EU/μg of the protein by LAL method.
• Immunogen DescriptionAla302-Ser414
• Target NameTGFb2
• Alternative Names    Human Transforming growth factor beta-2 proprotein;Cetermin Glioblastomaderived T-cell suppressor factor1 Short name: G-TSF
• Accession No. Uniprot:P61812
  Gene ID:7042
  #NP:NC_000001.11
• UniprotP61812
• Gene ID7042
• Target Species human
• Calculated MW 12.8 KDa
• Tag Info additional amino acid free
• Formulation 0.22 μm filtered solution of citric acid,PH2.5.
• Reconstitution 0.1 mg/mL in sterile citric acid,PH2.5
• Storage Aliquot and store at -80˚C. Avoid repeated freeze/thaw cycles.

TGF-beta 2 (transforming growth factor beta 1) is one of three closely related mammalian members of the large TGF-beta superfamily that share a characteristic cystine knot structure . TGF-beta 1, -2 and -3 are highly pleiotropic cytokines that are proposed to act as cellular switches that regulate processes such as immune function, proliferation and epithelial-mesenchymal transition . Each TGF-beta isoform has some non?redundant functions; the TGFB2 gene, which encodes transforming growth factor ��2 (TGF��2), making it an obvious candidate gene for this aneurysm phenotype with MFS- and LDS-like features.Human TGF? beta 2 cDNA encodes a 414 amino acid (aa) precursor that contains a 20 aa signal peptide and a 394 aa proprotein . A furin?like convertase processes the proprotein to generate an N?terminal 282 aa latency?associated peptide (LAP) and a C?terminal 112 aa mature TGF? beta 2 .

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting