• Product NameRecombinant human TGFb3
• Host SpeciesHEK293
• Purification> 95% by Tris-Bis
• Biological ActivityMeasured by the CAGA-luciferase reporter assay.. ED50: 0.268 ng/mL.
• Endotoxin< 4 EU/μg of the protein by LAL method.
• Immunogen DescriptionAla300-Ser412
• Target NameTGFb3
• Alternative Names    Transforming growth factor beta3 proprotein;TGF-beta-3
• Accession No. Uniprot:P10600
  Gene ID:7043
  #NP:NC_000014
• UniprotP10600
• Gene ID7043
• Target Species human
• Calculated MW 12.8 KDa
• Tag Info additional amino acid free
• Formulation 0.22 μm filtered solution of citric acid,PH2.5.
• Reconstitution 0.2mg/mL in sterile citric acid,PH2.5
• Storage Aliquot and store at -80˚C. Avoid repeated freeze/thaw cycles.

TGF-beta 3 (transforming growth factor beta 1) is one of three closely related mammalian members of the large TGF-beta superfamily that share a characteristic cystine knot structure . TGF-beta 1, -2 and -3 are highly pleiotropic cytokines that are proposed to act as cellular switches that regulate processes such as immune function, proliferation and epithelial-mesenchymal transition . Each TGF-beta isoform has some non?redundant functions; .Human TGF? beta 3 cDNA encodes a 412 amino acid (aa) precursor that contains a 23 aa signal peptide and a 389 aa proprotein . A furin?like convertase processes the proprotein to generate an N?terminal 277 aa latency?associated peptide (LAP) and a C?terminal 112 aa mature TGF? beta 3.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting