• Product Namegp120 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAffinity chromatography purified via peptide column
• ApplicationsELISA WB
• Species ReactivityVirus
• Immunogen TypePeptide
• Immunogen DescriptionRaised against 16 amino acid peptide representing the major HIV-1 consensus sequence near the N-terminal region of V1/V2 loop.
• Target Namegp120
• Alternative Names    HIV-1 glycoprotein 120
• Accession No. Swiss-Prot:Q6BBS3
  Gene ID:
• UniprotQ6BBS3
• Concentration 1mg/ml
• Formulation Supplied in PBS containing 0.02% sodium azide.
• Storage Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.

• Western blot analysis of 5 ng of gp120 with gp120 antibody at 1 μg/mL.
• Western blot analysis of 1 ug of gp120 with gp120 antibody at (A) 0.5 and (B) 1 ug/mL.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting