• Product NameIL-17 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAffinity chromatography purified via peptide column
• ApplicationsELISA WB
• Species ReactivityHu Ms
• Immunogen TypePeptide
• Immunogen DescriptionRaised against a 19 amino acid peptide from near the center of human IL-17A.
• Target NameIL-17
• Alternative Names    Interleukin-17, IL-17A, CTLA8
• Accession No. Swiss-Prot:Q16552
  Gene ID:3605
• UniprotQ16552
• Gene ID3605;
• Concentration 1mg/ml
• Formulation Supplied in PBS containing 0.02% sodium azide.
• Storage Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.

Interleukin 17 (IL-17) is a family of pro-inflammatory cytokines produced by activated T cells and is thought to have a major role in the initiation and perpetuation of rheumatoid arthritis. IL-17 regulates the activities of NF-κB and mitogen-activated protein kinases such as ERK and JNK. In addition, IL-17 stimulates the expression of IL-6 and cyclooxygenase-2 and enhances the production of nitric oxide. IL-17-producing T helper cells (TH-17 cells) have been the subject of much attention due to the importance of IL-17 in the pathogenesis of autoimmune inflammation. Because of its role in autoimmune diseases, it is thought that targeting the production and action of IL-17 would be beneficial therapeutically in these diseases.

• Western blot analysis of IL-17 in A-20 lysate with IL-17 antibody at (A) 0.5 and (B) 1 ug/mL.
• Western blot analysis of IL-17 in A-20 cell lysate with IL-17 antibody at (A) 2 and (B) 4 μg/mL.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting