• Product NameLRFN4 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAffinity chromatography purified via peptide column
• ApplicationsELISA WB IHC
• Species ReactivityHu Ms Rt
• SpecificityThis antibody is predicted to not cross-react with other members of the LRFN family.
• Immunogen TypePeptide
• Immunogen DescriptionRaised against a 14amino acid peptide near the carboxy terminus of human LRFN4.
• Target NameLRFN4
• Alternative Names    Leucine-rich repeat and fibronectin typeIII domain-containing protein 4, synaptic adhesion-like molecule 3, SALM3, FIGLER6
• Accession No. Q6PJG9
• UniprotQ6PJG9
• Gene ID78999;
• Concentration 1mg/ml
• Formulation Supplied in PBS containing 0.02% sodium azide.
• Storage Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

LRFN4 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system. At least two isoforms of LRFN4 are known to exist.

• Western blot analysis of LRFN4 in rat brain lysate with LRFN4 antibody at 1 ug/mL.
• Immunohistochemistry of LRFN4 in mouse brain tissue with LRFN4 antibody at 2.5 ug/mL.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting