• Product NameCRTC3 Rabbit mAb
• Host SpeciesRecombinant Rabbit
• ClonalityMonoclonal antibody
• Clone No.S07-4C9
• IsotypeRabbit IgG
• PurificationAffinity Purified
• ApplicationsWB
• Species ReactivityHuman,Mouse,Rat
• Immunogen DescriptionA synthetic peptide of human CRTC3
• ConjugatesUnconjugated
• ModificationUnmodification
• Alternative Names    TORC3; FLJ21868; CRTC3
• Accession No. Swiss-Prot:Q6UUV7
  GeneID:64784
• UniprotQ6UUV7
• Gene ID64784
• Calculated MW Calculated MW: 67 kDa; Observed MW: 78 kDa
• Concentration 0.3 mg/ml
• Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Storage Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

• WB: 1/2000;

Swiss-Prot Acc.Q6UUV7.Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).

• Western blot detection of CRTC3 in K562,Rat Brain,C6,3T3,Hela cell lysates using CRTC3 Rabbit mAb(1:1000 diluted).Predicted band size:67kDa.Observed band size:78kDa.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting