• Product NameLRP1 Rabbit mAb
• Clone No.S09-4E8
• IsotypeRabbit IgG
• PurificationAffinity Purified
• ApplicationsWB,IHC,ICC/IF,IP,FC
• Species ReactivityHuman,Mouse,Rat
• Immunogen DescriptionA synthetic peptide of human LRP1
• ConjugatesUnconjugated
• ModificationUnmodification
• Alternative Names    A2MR; alpha 2MR; Alpha 2 macroglobulin receptor; CD91; APR; LRP1; LRP85; TGFBR5;
• Accession No. Swiss-Prot:Q07954
  GeneID:4035
• UniprotQ07954
• Gene ID4035
• Calculated MW Calculated MW: 85 kDa; Observed MW: 85 kDa
• Concentration 0.3 mg/ml
• Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

• WB 1:10000-1:20000 IHC 1:50-1:100 ICC/IF 1:50-1:100 IP 1:30 FC 1:50

Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission.Functions as a receptor for Pseudomonas aeruginosa exotoxin A.

• Western blot detection of LRP1 in Rat Brain,C6 cell lysates using LRP1 Rabbit mAb(1:1000 diluted).Predicted band size:85kDa.Observed band size:85kDa.
• Immunohistochemistry of LRP1 in paraffin-embedded Human Cholangiocarcinoma using LRP1 Rabbit mAb at dilution 1/20
• All lanes use the Antibody at 1:3W dilution for 1 hour at room temperature.
• Immunohistochemical analysis of paraffin-embedded Human pituitary tumor, using the Antibody at 1:300 dilution.
• 

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting