• Product NameTBK1 Rabbit mAb
• Host SpeciesRecombinant Rabbit
• ClonalityMonoclonal antibody
• Clone No.S01-1G3
• IsotypeRabbit IgG
• PurificationAffinity Purified
• ApplicationsWB
• Species ReactivityHuman,Mouse,Rat
• Immunogen DescriptionA synthetic peptide of human TBK1
• ConjugatesUnconjugated
• ModificationUnmodification
• Alternative Names    NAK; T2K; NF-kappa-B-activating kinase; TANK-binding kinase 1; Serine/threonine-protein kinase TBK1; T2K; TANK binding kinase 1;
• Accession No. Swiss-Prot:Q9UHD2
  GeneID:29110
• UniprotQ9UHD2
• Gene ID29110
• Calculated MW Calculated MW: 84 kDa; Observed MW: 84 kDa
• Concentration 0.3 mg/ml
• Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Storage Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

• WB: 1/1000;

Swiss-Prot Acc.Q9UHD2. Phosphorylated IRF3 dissociates from the adapter proteins, dimerizes, and then enters the nucleus to induce expression of interferons (PubMed:25636800). Thus, several scaffolding molecules including FADD, TRADD, MAVS, AZI2, TANK or TBKBP1/SINTBAD can be recruited to the TBK1-containing-complexes (PubMed:21931631). Under particular conditions, functions as a NF-kappa-B effector by phosphorylating NF-kappa-B inhibitor alpha/NFKBIA, IKBKB or RELA to translocate NF-Kappa-B to the nucleus

• Western blot detection of TNK1/NAK in Jurkat,C6,CHO-K1,Hela cell lysates using TNK1/NAK Rabbit mAb(1:1000 diluted).Predicted band size:84kDa.Observed band size:84kDa.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting