• Product NameABCG1 Rabbit mAb
• Host SpeciesRecombinant Rabbit
• ClonalityMonoclonal antibody
• Clone No.S06-5B9
• IsotypeRabbit IgG
• PurificationAffinity Purified
• ApplicationsWB
• Species ReactivityHuman,Mouse,Rat
• Immunogen DescriptionA synthetic peptide of human ABCG1
• ConjugatesUnconjugated
• ModificationUnmodification
• Alternative Names    ATP-binding cassette transporter 8; White protein homolog; ABC8; WHT1;ABCG1; ABC transporter 8; WHITE1;
• Accession No. Swiss-Prot:P45844
  GeneID:9619
• UniprotP45844
• Gene ID9619
• Calculated MW Calculated MW: 76 kDa; Observed MW: 100 kDa
• Concentration 0.3 mg/ml
• Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Storage Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

• WB: 1/2000

Catalyzes the efflux of phospholipids such as sphingomyelin, cholesterol and its oxygenated derivatives like 7beta-hydroxycholesterol and this transport is coupled to hydrolysis of ATP (PubMed:17408620, PubMed:24576892). The lipid efflux is ALB-dependent (PubMed:16702602). Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages. Prevents cell death by transporting cytotoxic 7beta-hydroxycholesterol (PubMed:17408620).

• Western blot detection of ABCG1 in Hela cell lysates using ABCG1 Rabbit mAb(1:1000 diluted).Predicted band size:76kDa.Observed band size:100kDa.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting