• Product Namep16 ARC Rabbit mAb
• Host SpeciesRecombinant Rabbit
• ClonalityMonoclonal antibody
• Clone No.S08-2B3
• IsotypeRabbit IgG
• PurificationAffinity Purified
• ApplicationsWB IHC
• Species ReactivityHuman,Mouse,Rat
• Immunogen DescriptionA synthetic peptide of human p16 ARC
• ConjugatesUnconjugated
• ModificationUnmodification
• Alternative Names    Arp2/3 complex 16 kDa subunit;p16-ARC
• Accession No. Swiss-Prot:O15511
  GeneID:10092
• UniprotO15511
• Gene ID10092
• Calculated MW Calculated MW: 16 kDa; Observed MW: 16 kDa
• Concentration 0.3 mg/ml
• Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Storage Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

• WB: 1/2000;

Swiss-Prot Acc.O15511.Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947).

• Western blot detection of p16 ARC in Rat Brain,C6,3T3,Hela cell lysates using p16 ARC Rabbit mAb(1:1000 diluted).Predicted band size:16kDa.Observed band size:16kDa.
• Immunohistochemistry of p16 ARC in paraffin-embedded Human Cholangiocarcinoma using p16 ARC Rabbit mAb at dilution 1/20

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting