• Product NameBACE1 Rabbit mAb
• Host SpeciesRecombinant Rabbit
• ClonalityMonoclonal antibody
• Clone No.S03-9C8
• IsotypeRabbit IgG
• PurificationAffinity Purified
• ApplicationsWB
• Species ReactivityMouse,Rat
• Immunogen DescriptionRecombinant protein of mouse BACE1
• ConjugatesUnconjugated
• ModificationUnmodification
• Alternative Names    ASP2; Bace; C76936
• Accession No. Swiss-Prot:P56818
  GeneID:23821
• UniprotP56818
• Gene ID23821
• Calculated MW Calculated MW: 56 kDa; Observed MW: 70 kDa
• Concentration 0.3 mg/ml
• Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Storage Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

• WB: 1/1000;

Swiss-Prot Acc.P56818.Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. Cleaves APP with much more catalytic efficiency than for the wild-type.

• Western blot detection of BACE1 in Rat Brain lysates using BACE1 Rabbit mAb(1:1000 diluted).Predicted band size:56kDa.Observed band size:70kDa.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting