• Product NameFADD Rabbit mAb
• Host SpeciesRecombinant Rabbit
• ClonalityMonoclonal antibody
• Clone No.S05-1K1
• IsotypeRabbit IgG
• PurificationAffinity Purified
• ApplicationsWB
• Species ReactivityMouse
• Immunogen DescriptionA synthetic peptide of mouse FADD
• ConjugatesUnconjugated
• ModificationUnmodification
• Alternative Names    Mort1/FADD
• Accession No. Swiss-Prot:Q61160
  GeneID:14082
• UniprotQ61160
• Gene ID14082
• Calculated MW Calculated MW: 23 kDa; Observed MW: 28 kDa
• Concentration 0.3 mg/ml
• Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Storage Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

• WB: 1/1000-1/5000;

Swiss-Prot Acc.Q61160.Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis . Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling .

• Western blot detection of FADD in SHSY-5Y cell lysates using FADD Rabbit mAb(1:1000 diluted).Predicted band size:23KDa.Observed band size:28KDa.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting