• Product NameITPA Rabbit mAb
• Host SpeciesRecombinant Rabbit
• ClonalityMonoclonal antibody
• Clone No.S01-4D4
• IsotypeRabbit IgG
• PurificationAffinity Purified
• ApplicationsWB IHC
• Species ReactivityHuman
• Immunogen DescriptionA synthetic peptide of human Inosine triphosphate pyrophosphatase
• ConjugatesUnconjugated
• ModificationUnmodification
• Alternative Names    My049; ITPase; NTPase; C20orf37; dJ794I6.3; HLC14-06-P
• Accession No. Swiss-Prot:Q9BY32
  GeneID:3704
• UniprotQ9BY32
• Gene ID3704
• Calculated MW Calculated MW: 22 kDa; Observed MW: 22 kDa
• Concentration 0.3 mg/ml
• Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Storage Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

• WB: 1/1000-1/5000; IHC: 1/20-1/50

Swiss-Prot Acc.Q9BY32.Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.

• Western blot detection of ITPA in Hela cell lysates using ITPA Rabbit mAb(1:1000 diluted).Predicted band size:22kDa.Observed band size:22kDa.
• Immunohistochemistry of Inosine triphosphate pyrophosphatase in paraffin-embedded Human breast cancer tissue using Inosine triphosphate pyrophosphatase Rabbit mAb at dilution 1/50

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting