• Product NamePhospholipase A2 Activator Protein Rabbit mAb
• Host SpeciesRecombinant Rabbit
• ClonalityMonoclonal antibody
• Clone No.S06-1D7
• IsotypeRabbit IgG
• PurificationAffinity Purified
• ApplicationsWB
• Species ReactivityHuman
• Immunogen DescriptionA synthetic peptide of human Anti-Phospholipase A2 activator protein (PLAP)
• ConjugatesUnconjugated
• ModificationUnmodification
• Alternative Names    DOA1; PLAP; PLA2P; NDMSBA
• Accession No. Swiss-Prot:Q9Y263
  GeneID:9373
• UniprotQ9Y263
• Gene ID9373
• Calculated MW Calculated MW: 87 kDa; Observed MW: 87 kDa
• Concentration 0.3 mg/ml
• Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Storage Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

• WB: 1/1000;

Swiss-Prot Acc.Q9Y263.Plays a role in protein ubiquitination, sorting and degradation through its association with VCP (PubMed:27753622). Involved in ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner, and hence plays a role in synaptic vesicle recycling . May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes (PubMed:27753622). Plays a role in cerebellar Purkinje cell development . Positively regulates cytosolic and calcium-independent phospholipase A2 activities in a tumor necrosis factor alpha (TNF-alpha)- or lipopolysaccharide (LPS)-dependent manner, and hence prostaglandin E2 biosynthesis (PubMed:18291623, PubMed:28007986).

• Western blot detection of Phospholipase A2 activator protein (PLAP) in 3T3,Hela cell lysates using Phospholipase A2 activator protein (PLAP) Rabbit mAb(1:1000 diluted).Predicted band size:87kDa.Observed band size:87kDa.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting