• Product NameWAVE 1 Rabbit mAb
• Host SpeciesRecombinant Rabbit
• ClonalityMonoclonal antibody
• Clone No.S03-5K1
• IsotypeRabbit IgG
• PurificationAffinity Purified
• ApplicationsWB
• Species ReactivityHuman,Mouse,Rat
• Immunogen DescriptionRecombinant protein of human WAVE 1
• ConjugatesUnconjugated
• ModificationUnmodification
• Alternative Names    WAVE; SCAR1; WAVE1
• Accession No. Swiss-Prot:Q92558
  GeneID:8936
• UniprotQ92558
• Gene ID8936
• Calculated MW Calculated MW: 62 kDa; Observed MW: 90 kDa
• Concentration 0.3 mg/ml
• Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Storage Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

• WB: 1/1000-1/5000;

Swiss-Prot Acc.Q92558.Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex . As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes .

• Western blot detection of WAVE 1 in Rat Brain,C6,3T3,Hela cell lysates using WAVE 1 Rabbit mAb(1:1000 diluted).Predicted band size:62kDa.Observed band size:90kDa.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting