• Product NameWDR5 Rabbit mAb
• Host SpeciesRecombinant Rabbit
• ClonalityMonoclonal antibody
• Clone No.S05-4D3
• IsotypeRabbit IgG
• PurificationAffinity Purified
• ApplicationsWB
• Species ReactivityHuman,Mouse,Rat
• Immunogen DescriptionA synthetic peptide of human WDR5
• ConjugatesUnconjugated
• ModificationUnmodification
• Alternative Names    SWD3; BIG-3; CFAP89
• Accession No. Swiss-Prot:P61964
  GeneID:11091
• UniprotP61964
• Gene ID11091
• Calculated MW Calculated MW: 37 kDa; Observed MW: 37 kDa
• Concentration 0.3 mg/ml
• Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Storage Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

• WB: 1/1000;

Swiss-Prot Acc.P61964.Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.

• Western blot detection of WDR5 in K562,C6,3T3,Hela cell lysates using WDR5 Rabbit mAb(1:1000 diluted).Predicted band size:37kDa.Observed band size:37kDa.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting