• Product NamePhospho-TrkB (Tyr705) Rabbit mAb
• Host SpeciesRecombinant Rabbit
• ClonalityMonoclonal antibody
• Clone No.S04-6B1
• IsotypeIgG
• PurificationAffinity Purified
• ApplicationsWB
• Species ReactivityHuman,Mouse,Rat
• Immunogen DescriptionA synthetic phosphopeptide corresponding to residues surrounding Tyr705 of human TrkB
• ConjugatesUnconjugated
• ModificationPhosphorylated
• Alternative Names    OBHD; TRKB; trk-B; EIEE58; GP145-TrkB
• Accession No. Swiss-Prot:Q16620
  GeneID:4915
• UniprotQ16620
• Gene ID4915
• Calculated MW Calculated MW:92 kDa,Observed MW:140,90 kDa
• Concentration 0.3 mg/ml
• Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Storage Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

• WB: 1/1000

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

• Western blot detection of phospho-TrkB (Tyr705) in Hela,A549,C6 cell lysates using phospho-TrkB (Tyr705) Rabbit mAb(1:1000 diluted).Predicted band size:92kDa.Observed band size:140,90kDa.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting