• Product NameNectin 2 Rabbit mAb
• Host SpeciesRecombinant Rabbit
• ClonalityMonoclonal antibody
• Clone No.S07-7G6
• IsotypeIgG
• PurificationAffinity Purified
• ApplicationsWB
• Species ReactivityHuman
• Immunogen DescriptionRecombinant protein of human Nectin 2
• ConjugatesUnconjugated
• ModificationUnmodification
• Alternative Names    HVEB; PRR2; CD112; PVRL2; PVRR2
• Accession No. Swiss-Prot:Q92692
  GeneID:5819
• UniprotQ92692
• Gene ID5819
• Calculated MW Calculated MW:58 kDa,Observed MW:70-80 kDa
• Concentration 0.3 mg/ml
• Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Storage Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

• WB: 1/1000

Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive (PubMed:26755705). Probable cell adhesion protein (PubMed:9657005).

• Western blot detection of Nectin 2 in Hela,A549,U2OS,U87-MG cell lysates using Nectin 2 Rabbit mAb(1:1000 diluted).Predicted band size:58kDa.Observed band size:70-80kDa.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting