• Product NameRSK2 Rabbit mAb
• Host SpeciesRecombinant Rabbit
• ClonalityMonoclonal antibody
• Clone No.S05-6E3
• IsotypeIgG
• PurificationAffinity Purified
• ApplicationsWB IHC
• Species ReactivityHuman,Mouse,Rat
• Immunogen DescriptionA synthetic peptide of human Rsk 2/MAPKAP Kinase 1b
• ConjugatesUnconjugated
• ModificationUnmodification
• Alternative Names    CLS; RSK; HU-3; RSK2; MRX19; ISPK-1; p90-RSK2; pp90RSK2; MAPKAPK1B; S6K-alpha3
• Accession No. Swiss-Prot:P51812
  GeneID:6197
• UniprotP51812
• Gene ID6197
• Calculated MW Calculated MW:84 kDa,Observed MW:84 kDa
• Concentration 0.3 mg/ml
• Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Storage Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

• WB: 1/2000 IHC: 1/20

Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular proliferation, survival, and differentiation by modulating mTOR signaling and repressing pro-apoptotic function of BAD and DAPK1 (PubMed:9770464, PubMed:16223362, PubMed:17360704, PubMed:16213824).

• Western blot detection of Rsk 2/MAPKAP Kinase 1b in CHO-K1,Ramos using Rsk 2/MAPKAP Kinase 1b Rabbit mAb(1:1000 diluted)
• Immunohistochemistry of Rsk 2/MAPKAP Kinase 1b in paraffin-embedded Human lung cancer tissue using Rsk 2/MAPKAP Kinase 1b Rabbit mAb at dilution 1/50

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting