• Product NameRecombinant Human B cell Activating Factor Rececptor/TNFRSF13C
• Host SpeciesEscherichia coli.
• Purification> 95 % by reduced SDS-PAGE analyses.
• Biological ActivityFully biologically active when compared to standard. The ED50 as determined by a mouse splenocyte survival assay is 0.5-2 μg/ml.
• EndotoxinLess than 1 EU/ug of rHuBAFF-R as determined by LAL method.
• Alternative Names    BAFFR, TNFRSF13C
• UniprotQ96RJ3
• Gene ID115650
• Calculated MW Approximately 7.8 kDa, a single non-glycosylated polypeptide chain containing 76 amino acids.
• Target Sequence MRRGPRSLRG RDAPAPTPCV PAECFDLLVR HCVACGLLRT PRPKPAGASS PAPRTALQPQ ESVGAGAGEA ALPLPG
• Formulation Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.0.
• Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 ˚C as supplied.- 1 month, 2 to 8 ˚C under sterile conditions after reconstitution.- 3 months, -20 to -70 ˚C under sterile conditions after reconstitution.

B Cell Activating Factor Receptor (BAFF-R), also named tumor necrosis factor receptor superfamily member 13C, is a member of the TNFR superfamily. It is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFF receptor is a type III transmembrane protein containing a single extracellular phenylalanine-rich domain and binds with high specificity to BAFF (TNFSF13B). It enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. BAFF receptor/BAFF signaling plays a critical role in B cell survival and maturation.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting