- Product NameRecombinant Human 4-1BB Receptor/TNFRSF9
- Host SpeciesEscherichia coli.
- Purification> 97 % by SDS-PAGE and HPLC analyses.
- Biological ActivityFully biologically active when compared to standard. The biological activity is determined by its inhibitory effect of IL-8 production using human peripheral blood mononuclear cells. About 90 % of inibition was seen using a concentration of 1 μg for both 4-1BB Ligand and 4-1BB Receptor.
- EndotoxinLess than 1 EU/ug of rHu4-1BB Receptor as determined by LAL method.
- Alternative Names TNFRSF9, CD137 Antigen, T-cell Antigen ILA
- UniprotQ07011
- Gene ID3604
- Calculated MW Approximately 17.7 kDa, a single non-glycosylated polypeptide chain containing 166 amino acids.
- Target Sequence ERTRSLQDPC SNCPAGTFCD NNRNQICSPC PPNSFSSAGG QRTCDICRQC KGVFRTRKEC SSTSNAECDC TPGFHCLGAG CSMCEQDCKQ GQELTKKGCK DCCFGTFNDQ KRGICRPWTN CSLDGKSVLV NGTKERDVVC GPSPADLSPG ASSVTPPAPA REPGHS
- Formulation Lyophilized from a 0.2 μm filtered concentrated solution in 10 mM PB, pH 8.0, 150 mM NaCl.
- Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 ˚C as supplied.- 1 month, 2 to 8 ˚C under sterile conditions after reconstitution.- 3 months, -20 to -70 ˚C under sterile conditions after reconstitution.
