- Product NameRecombinant Human Neuregulin 1-beta1 EGF Domain, 177-241a.a.
- Host SpeciesEscherichia coli.
- Purification> 97 % by SDS-PAGE and HPLC analyses.
- Biological ActivityFully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using serum free human MCF-7 cells is less than 0.5 ng/ml, corresponding to a specific activity of �� 2.0 x106IU/mg.
- EndotoxinLess than 0.1 EU/ug of rHuNRG1-β1, 177-241a.a. as determined by LAL method.
- UniprotQ02297
- Gene ID3084
- Calculated MW Approximately 7.5 kDa, a single non-glycosylated polypeptide chain containing 65 amino acids.
- Target Sequence SHLVKCAEKE KTFCVNGGEC FMVKDLSNPS RYLCKCPNEF TGDRCQNYVM ASFYKHLGIE FMEAE
- Formulation Lyophilized from a 0.2 μm filtered solution in 1 x PBS, pH 7.4, with 5 % trehalose.
- Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 ˚C as supplied.- 1 month, 2 to 8 ˚C under sterile conditions after reconstitution.- 3 months, -20 to -70 ˚C under sterile conditions after reconstitution.
