- Product NameRecombinant Rat Interleukin-17A
- Host SpeciesEscherichia coli.
- Purification> 95 % by SDS-PAGE and HPLC analyses.
- Biological ActivityFully biologically active when compared to standard. The ED50 as determined by inducing IL-6 secretion of murine NIH/3T3 cells is less than 1.0 ng/ml, corresponding to a specific activity of > 1.0 x106 IU/mg.
- EndotoxinLess than 0.1 EU/ug of rRtIL-17A as determined by LAL method.
- UniprotQ61453
- Calculated MW Approximately 30.0 kDa, a disulfide-linked homodimer of two 133 amino acid polypeptide chains.
- Target Sequence AVLIPQSSVC PNAEANNFLQ NVKVNLKVIN SLSSKASSRR PSDYLNRSTS PWTLSRNEDP DRYPSVIWEA QCRHQRCVNA EGKLDHHMNS VLIQQEILVL KREPEKCPFT FRVEKMLVGV GCTCVSSIVR HAS
- Formulation Lyophilized from a 0.2 μm filtered concentrated solution in 2 x PBS, pH 6.5.
- Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 ˚C as supplied.- 1 month, 2 to 8 ˚C under sterile conditions after reconstitution.- 3 months, -20 to -70 ˚C under sterile conditions after reconstitution.
