• Product NameCD46 Rabbit mAb
• Host SpeciesRabbit
• ClonalityMonoclonal
• IsotypeRabbit IgG
• PurificationAffinity-chromatography
• ApplicationsWB IHC ICC/IF
• Species ReactivityHuman
• SpecificityCD46 Antibody detects endogenous levels of total CD46
• Immunogen DescriptionA synthesized peptide derived from human CD46
• Alternative Names    MCP; MIC10; TLX; TRA2.10; CD46;
• Accession No. Uniprot:P15529
• UniprotP15529
• Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

• WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

• CD46 is a type I membrane protein and a regulatory part of the complement system. This protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, CD46 can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria.

CD46 is a type I membrane protein and a regulatory part of the complement system. This protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, CD46 can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria.

• Western blot analysis of CD46 in K562 cell lysate.
• Immunohistochemical analysis of paraffin-embedded human colon, using CD46 Antibody.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting