• Product NameAlpha Synuclein Rabbit mAb
• Host SpeciesRabbit
• ClonalityMonoclonal
• IsotypeRabbit IgG
• PurificationAffinity-chromatography
• ApplicationsWB IHC ICC/IF IP FC
• Species ReactivityHuman
• SpecificityAlpha Synuclein Antibody detects endogenous levels of total Alpha Synuclein
• Immunogen DescriptionA synthesized peptide derived from human Alpha Synuclein
• Alternative Names    Alpha-synuclein; NACP; non A-beta component of AD amyloid; Non-A beta component of AD amyloid; PARK1; PARK4; PD1; SNCA;
• Accession No. Uniprot:P37840
• UniprotP37840
• Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

• WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50

• May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. Genetic alterations of SNCA resulting in aberrant polymerization into fibrils, are associated with several neurodegenerative diseases (synucleinopathies).

May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. Genetic alterations of SNCA resulting in aberrant polymerization into fibrils, are associated with several neurodegenerative diseases (synucleinopathies).

• Western blot analysis of Alpha Synuclein expression in Human fetal brain lysate.
• Immunohistochemical analysis of paraffin-embedded mouse testis, using Alpha Synuclein Antibody.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting