• Product NamePBR Rabbit mAb
• Host SpeciesRabbit
• ClonalityMonoclonal
• IsotypeRabbit IgG
• PurificationAffinity-chromatography
• ApplicationsWB IHC ICC/IF IP FC
• Species ReactivityHuman Mouse
• SpecificityPBR Antibody detects endogenous levels of total PBR
• Immunogen DescriptionA synthesized peptide derived from human PBR
• Alternative Names    TSPO; PBR; BZRP; IBP; MBR; PKBS; Mitochondrial benzodiazepine receptor; Peripheral benzodiazepine receptor;
• Accession No. Uniprot:P30536
• UniprotP30536
• Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

• WB 1:5000~1:10000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50

• Peroxisome proliferator perfluordecanoic acid (PFDA) inhibits the Leydig cell steroidogenesis by affecting PBR mRNA stability, thus inhibiting PBR expression, cholesterol transport into the mitochondria and subsequent steroid formation. A cytoplasmic protein, PRAX-1 ��peripheral benzodiazepine receptor-associated protein 1), is found to specifically interact with PBR.

Peroxisome proliferator perfluordecanoic acid (PFDA) inhibits the Leydig cell steroidogenesis by affecting PBR mRNA stability, thus inhibiting PBR expression, cholesterol transport into the mitochondria and subsequent steroid formation. A cytoplasmic protein, PRAX-1 ��peripheral benzodiazepine receptor-associated protein 1), is found to specifically interact with PBR.

• Western blot analysis of Calreticulin expression in (1) U87-MG cell lysate; (2) A431 cell lysate.
• Immunohistochemical analysis of paraffin-embedded human colon, using PBR Antibody .

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting