• Product Name53BP1 Rabbit mAb
• Host SpeciesRabbit
• ClonalityMonoclonal
• IsotypeRabbit IgG
• PurificationAffinity-chromatography
• ApplicationsWB IHC ICC/IF FC
• Species ReactivityHuman Mouse Rat
• Specificity53BP1 Antibody detects endogenous levels of total 53BP1
• Immunogen DescriptionA synthesized peptide derived from human 53BP1
• Alternative Names    Tumor suppressor p53-binding protein 1; 53 BP1; p53-binding protein 1; p53BP1; TP53BP1; p53-BP1; p202;
• Accession No. Uniprot:Q12888
• UniprotQ12888
• Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

• WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50

• May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation. Plays a role in the response to DNA damage.

May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation. Plays a role in the response to DNA damage.

• Western blot analysis of 53BP1 expression in HeLa cell lysate.
• Immunohistochemical analysis of paraffin-embedded mouse liver, using 53BP1 Antibody.
• Immunofluorescent analysis of HepG2 cells, using 53BP1 Antibody .

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting