• Product NameActivin Receptor Type IIB/ACVR2B Rabbit mAb
• Host SpeciesRabbit
• ClonalityMonoclonal
• IsotypeRabbit IgG
• PurificationAffinity-chromatography
• ApplicationsWB
• Species ReactivityHuman Mouse Rat
• SpecificityActivin Receptor Type IIB Antibody detects endogenous levels of total Activin Receptor Type IIB
• Immunogen DescriptionA synthesized peptide derived from human Activin Receptor Type IIB
• Alternative Names    ActR IIB; ACVR 2B; HTX4;
• Accession No. Uniprot:Q13705
• UniprotQ13705
• Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

• WB 1:500~1:2000

• On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.

• Western blot analysis of Activin Receptor Type IIB/ACVR2B expression in (1) K562 cell lysate; (2) Mouse heart lysate.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting