• Product NameTDP43 Rabbit mAb
• Host SpeciesRabbit
• ClonalityMonoclonal
• IsotypeRabbit IgG
• PurificationAffinity-chromatography
• ApplicationsWB IHC ICC/IF FC
• Species ReactivityHuman Mouse Rat
• SpecificityTDP43 Antibody detects endogenous levels of total TDP43
• Immunogen DescriptionA synthesized peptide derived from TDP43
• Alternative Names    ALS10; TAR DNA binding protein 43; TARDBP; TDP43;
• Accession No. Uniprot:Q13148
• UniprotQ13148
• Calculated MW 45kDa
• Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

• WB 1:1000~1:5000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50

• DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis.

DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis.

• Western blot analysis of TDP43 expression in (1) HeLa cell lysate; (2) Mouse brain lysate; (3) Rat brain lysate.
• Immunohistochemical analysis of paraffin-embedded human glioma, using TDP43 Antibody.
• Immunofluorescent analysis of Hela cells, using TDP43 Antibody .
• All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting