• Product NameCXXC5 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAffinity chromatography purified via peptide column
• ApplicationsELISA WB IHC
• Species ReactivityHu Ms Rt
• SpecificityAt least two isoforms of CXXC5 are known to exist. CXXC5 antibody is predicted to not cross-react with other CXXC protein family members.
• Immunogen TypePeptide
• Immunogen DescriptionRaised against a 15 amino acid peptide near the amino terminus of human CXXC5.
• Target NameCXXC5
• Alternative Names    CXXC-type zinc finger protein 5, CF5, WID, RINF, HSPC195
• Accession No. Swiss-Prot:Q7LFL8
  Gene ID:51523
• UniprotQ7LFL8
• Gene ID51523;
• Concentration 1mg/ml
• Formulation Supplied in PBS containing 0.02% sodium azide.
• Storage Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

CXXC5 is zinc finger protein closely related to the DVL1-binding protein CXXC4 (also known as Idax), and like CXXC4 is thought to modulate the Wnt signaling pathway during development. CXXC5 is upregulated in neural stem cells upon BMP4 stimulation, leading to decreased levels of the Wnt-signaling target AXIN2 and facilitated the response of the stem cells to Wnt3a. Recent reports suggest CXXC5 transcription is activated by the Wilms tumor 1 (WT1) transcription factor, and together are involved in the WNT/beta-catenin pathway and play a role in embryonic kidney development.

• Western blot analysis of CXXC5 in human brain tissue lysate with CXXC5 antibody at 1 ug/mL.
• Immunohistochemistry of CXXC5 in human brain tissue with CXXC5 antibody at 2.5 ug/mL.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting