• Product NamePDE8B Antibody
• Brief DescriptionRabbit Polyclonal
• Host SpeciesRabbit
• ClonalityPolyclonal
• Purificationaffinity purified by Protein A
• ApplicationsIHC;ICC/IF
• Species Reactivity(predicted: Human, Mouse, Rat)
• SpecificityThe antibody detects endogenous level of total PDE8B protein
• Immunogen TypePeptide
• Immunogen DescriptionKLH conjugated synthetic peptide derived from human PDE8B
• UniprotO95263;
• Formulation 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Storage Shipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.

• IHC 1:100-500;ICC/IF 1:100-500

The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010]

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting