• Product NameZIMP7 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAffinity chromatography purified via peptide column
• ApplicationsELISA WB
• Species ReactivityHu Ms
• SpecificityAt least four isoforms are known to exist. ZIMP7 antibody is predicted to not cross-react with other PIAS protein family members.
• Immunogen TypePeptide
• Immunogen DescriptionRaised against a 17 amino acid peptide near the center of human ZIMP7.
• Target NameZIMP7
• Alternative Names    Zinc finger MIZ-type containing 2, ZMIZ2, TRAFIP20, PIAS-like protein Zimp7
• Accession No. Q8NF64
• UniprotQ8NF64
• Gene ID83637;
• Concentration 1mg/ml
• Formulation Supplied in PBS containing 0.02% sodium azide.
• Storage Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

ZIMP7, also known as ZMIZ2, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein and a transcriptional coactivator. ZIMP7 is expressed most abundantly in testis. The C-terminal proline-rich domain possesses a significant intrinsic transcriptional activity and this activity is inhibited by the N-terminus in the full-length ZIMP7. ZIMP7 and the related protein ZIMP10 interact with PIAS3 and enhances Androgen Receptor (AR)- mediated transcription. The interaction between ZIMP7 and SWI/SNF complex suggests a possible role for ZIMP7 in chromatin modification.

• Western blot analysis of ZIMP7 in A20 cell lysate with ZIMP7 antibody at (A) 0.25 ug/ml and (B) 0.5 ug/mL.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting