• Product NameBARK1 Monoclonal Antibody
• Host SpeciesMouse
• ClonalityMonoclonal
• Clone No.3F8-G6-C11
• IsotypeIgG1
• PurificationAffinity purified
• ApplicationsELISA WB
• Species ReactivityHu Rt Ms P D
• Immunogen TypeRecombinant protein
• Immunogen DescriptionPurified recombinant human ADRBK1(C-term.) protein fragments expressed in E.coli.
• Target NameBARK1
• Alternative Names    GRK2, BARK1, BETA-ARK1
• Accession No. Swiss-Prot:P13639
  Gene ID:1938
• UniprotP13639
• Gene ID1938;
• Formulation Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol

• Predicted MW: 80kd
  Western blotting: 1:1000
  

The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1.

• Western blot detection of ADRBK1 in U937,Raw264.7&Ramos whole cell lysate(1:1000 diluted)
  Predicted band size:80KDa.
  Observed band size:80KDa.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting