• Product NameTRAILR2 DR5 Antibody HRP Conjugated
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationPurified by Protein A.
• ApplicationsWB IHC-P IHC-F
• Species ReactivityHu Ms Rt
• Immunogen DescriptionKLH conjugated synthetic peptide aa 330-380 381 derived from mouse DR5
• ConjugatesHRP
• Excitation EmissionN A
• Target NameTRAILR2 DR5 CD262
• Alternative Names    MK; DR5; Ly98; KILLER; TRICKB; TRAILR2; TRICK2A; TRICK2B; Tumor necrosis factor receptor superfamily member 10B; Death receptor 5; CD262; Tnfrsf10b
• Accession No. Swiss-Prot#Q9QZM4
  NCBI Gene ID21933
• UniprotQ9QZM4
• Gene ID21933;
• Cell Localization Cytoplasm
• Concentration 1mg ml
• Formulation 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
• Storage Shipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.

• WB=1:500-2000 IHC-P=1:50-200 IHC-F=1:50-200

Receptor for the cytotoxic ligand TNFSF10 TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis (By similarity).

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting