• Product NamePDEF SPDEF Antibody HRP Conjugated
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationPurified by Protein A.
• Applications IHC-P IHC-F
• Species ReactivityHu Ms Rt
• Immunogen DescriptionKLH conjugated synthetic peptide derived from human PDEF
• ConjugatesHRP
• Excitation EmissionN A
• Target NamePDEF SPDEF
• Alternative Names    bA375E1.3; PDEF; Prostate derived Ets factor; PROSTATE EPITHELIUM SPECIC ETS TRANSCRIPTION FACTOR; Prostate epithelium-specic Ets transcription factor; Prostate specic Ets; Prostate-derived Ets factor; Prostate-specic Ets; PSE; RP11-375E1__A.3; SAM POINTED DOMAIN CONTAINING ETS TRANSCRIPTION FACTOR;
• Accession No.
  NCBI Gene ID25803
• UniprotO95238
• Gene ID25803;
• Concentration 1mg ml
• Formulation 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
• Storage Shipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.

• IHC-P=1:50-200 IHC-F=1:50-200

SPDEF, also known as PDEF is an ETS transcription factor expressed in the prostate epithelial cells. It is thought to act as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter and also as a transcriptional activator for the SERPINB5 promoter. It is highly expressed in prostate carcinoma cells and is thought to be involved in the regulation of the prostate gland and or prostate cancer development. It is also expressed in epithelial breast carcinoma.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting