• Product NameLymphocyte Activation Gene 3 Antibody HRP Conjugated
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationPurified by Protein A.
• ApplicationsWB  IHC-P IHC-F ICC
• Species ReactivityHu Ms Rt     
• Immunogen DescriptionKLH conjugated synthetic peptide aa 210-260 525 derived from human Lymphocyte Activation Gene 3
• ConjugatesHRP
• Excitation EmissionN A
• Target NameLymphocyte Activation Gene 3
• Alternative Names    CD223; Lymphocyte activation gene 3 protein; LAG-3; Lag3
• Accession No. Swiss-Prot#Q5BK54
  NCBI Gene ID297596
• UniprotQ5BK54
• Gene ID297596;
• Cell Localization Extracellular
• Concentration 1mg ml
• Formulation 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
• Storage Shipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.

• WB=1:500-2000  IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200

Lymphocyte-activation protein 3 (LAG-3), also known as CD223, belongs to the immunoglobulin superfamily and contains 4 extracellular Ig-like domains. LAG-3 binds to HLA class-II antigens and is involved in lymphocyte activation. It is found on the cell surface of activated NK and T-lymphocytes. The sequence data, exon intron organization, and chromosomal localization all indicate a close relationship of LAG-3 to CD4.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting