• Product NameFoxO3a (Phospho-Ser253) Antibody HRP Conjugated
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationPurified by Protein A.
• ApplicationsWB  IHC-P IHC-F
• Species ReactivityHu Ms Rt   
• Immunogen DescriptionKLH conjugated synthetic phosphopeptide aa 240-280 673 derived from human FoxO3a around the phosphorylation site of Ser253
• ConjugatesHRP
• Excitation EmissionN A
• Target NameFoxO3a Ser253
• Alternative Names    FOXO2; AF6q21; FKHRL1; FOXO3A; FKHRL1P2; Forkhead box protein O3; AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1; FOXO3
• Accession No. Swiss-Prot#O43524
  NCBI Gene ID2309
• UniprotO43524
• Gene ID2309;
• Cell Localization Cytoplasm, Nucleus
• Concentration 1mg ml
• Formulation 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
• Storage Shipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.

• WB=1:500-2000  IHC-P=1:50-200 IHC-F=1:50-200 

Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting