• Product NamePERK(Phospho-Thr980) Antibody FITC Conjugated
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationPurified by Protein A.
• ApplicationsFlow-Cyt IF
• Species ReactivityHu Ms Rt   
• Immunogen DescriptionKLH conjugated synthetic phosphopeptide aa 960-1010 1114 derived from mouse PERK around the phosphorylation site of Thr981
• ConjugatesFITC
• Excitation Emission494nm 518nm
• Target NamePERK Thr980
• Alternative Names    Pek; Perk; AI427929; Eukaryotic translation initiation factor 2-alpha kinase 3; PRKR-like endoplasmic reticulum kinase; Pancreatic eIF2-alpha kinase; Eif2ak3
• Accession No. Swiss-Prot#Q9Z2B5
  NCBI Gene ID13666
• UniprotQ9Z2B5
• Gene ID13666;
• Cell Localization Cytoplasm
• Concentration 1mg ml
• Formulation 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
• Storage Shipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.

• Flow-Cyt=1:50-200 IF=1:50-200

Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin-D1 (CCND1). Involved in control of mitochondrial morphology and function.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting