• Product NamePI3 kinase p85 alpha + gamma (Phospho-Tyr467 + Tyr199) antibody HRP Conjugated
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationPurified by Protein A.
• ApplicationsWB  IHC-P IHC-F
• Species ReactivityHu Ms Rt  
• Immunogen DescriptionKLH conjugated synthetic phosphopeptide aa 176-212 461 derived from human PI3K around the phosphorylation site of p85 alphaTyr467
• ConjugatesHRP
• Excitation EmissionN A
• Target NamePI3 kinase p85 alpha + gamma Tyr467 + Tyr199
• Alternative Names    p85; AGM7; GRB1; IMD36; p85-ALPHA; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns
• Accession No. Swiss-Prot#P27986
  NCBI Gene ID5295
• UniprotP27986
• Gene ID5295;
• Cell Localization Cytoplasm
• Concentration 1mg ml
• Formulation 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
• Storage Shipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.

• WB=1:500-2000  IHC-P=1:50-200 IHC-F=1:50-200 

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p11 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting