• Product NameZAP70 (Phospho-Tyr315 + Tyr319) Antibody HRP Conjugated
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationPurified by Protein A.
• ApplicationsWB  IHC-F
• Species ReactivityHu Ms   
• Immunogen DescriptionKLH conjugated synthetic phosphopeptide derived from human Zap-70 around the phosphorylation site of Tyr315 Tyr319
• ConjugatesHRP
• Excitation EmissionN A
• Target NameZAP70 Tyr315 + Tyr319
• Alternative Names    Zap-70Tyr315 Tyr319; Zap-70Y315 Y319; p-ZAP70 Tyr315 Tyr319; p-ZAP-70 Tyr315 Tyr319; p-ZAP70 Y315 Y319; ZAP-70; ZAP 70; ZAP70; zeta-associated protein 70; ZAP-70=protein tyrosine kinase Syk homolog {SH2-like and C-terminal kinase domains}; Tyrosine-protein kinase ZAP-70; 70 kDa zeta-associated prote
• Accession No.
  NCBI Gene ID7535
• UniprotP43403
• Gene ID7535;
• Concentration 1mg ml
• Formulation 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
• Storage Shipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.

• WB=1:500-2000  IHC-F=1:50-200 

This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting