• Product NamePTGER2 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• ApplicationsELISA WB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous level of total PTGER2 protein.
• Immunogen TypePeptide-KLH
• Immunogen DescriptionSynthetic peptide corresponding to a region derived from 1-13 amino acids of Human prostaglandin E receptor 2 (subtype EP2), 53kDa
• Target NamePTGER2
• Alternative Names    prostaglandin E receptor 2 (subtype EP2), 53kDa, EP2
• Accession No. Swiss-Prot:P43116
  Gene ID:5732;
• UniprotP43116
• Gene ID5732;
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C/1 year

• Predicted MW: 40kd
  ELISA: 1:1000-1:5000
  Western blotting: 1:500-1:2000

This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma. Prostaglandin E2 receptor?(53kDa), also known as?EP2, is a?prostaglandin receptor?for?prostaglandin E2. It is encoded by the human?gene?PTGER2. Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.

• Gel: 10%SDS-PAGE
  Lysate: 40 µg A549 cell lysate
  Primary antibody: 1/100 dilution
  Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution
  Exposure time: 1 minute

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting