• Product NameCLDN4 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• ApplicationsELISA WB IHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous level of total CLDN4 protein.
• Immunogen TypePeptide-KLH
• Immunogen DescriptionSynthetic peptide corresponding to a region derived from 193-209 amino acids of Human claudin 4
• Target NameCLDN4
• Alternative Names    claudin 4, CPER, CPE-R, CPETR, CPETR1, WBSCR8, hCPE-R
• Accession No. Swiss-Prot:O14493
  Gene ID:1364;
• UniprotO14493
• Gene ID1364;
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C/1 year

• Predicted MW: 22kd
  ELISA: 1:1000-1:10000
  Western blotting: 1:2000-1:5000
  Immunohistochemistry: 1:25-1:100

Claudin 4, also known as CLDN4, is a protein which in humans is encoded by the CLDN4 gene. It belongs to the group of claudins. This gene encodes an integral membrane protein, which belongs to the claudin family. The protein is a component of tight junction strands and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.

• Gel: 10%SDS-PAGE
  Lysate: 30 µg HT-29 cell lysate
  Primary antibody: 1/700 dilution
  Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution
  Exposure time: 30 seconds
• The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 31202 (CLDN4 Antibody) at dilution 1/35, on the right is treated with the synthetic peptide.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting