• Product NameP2RY12 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• ApplicationsELISA WB IHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous level of total P2RY12 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide corresponding to a region derived from 11-24 amino acids of human purinergic receptor P2Y, G-protein coupled, 12
• Target NameP2RY12
• Alternative Names    purinergic receptor P2Y, G-protein coupled, 12, HORK3, P2Y12, ADPG-R, BDPLT8, SP1999, P2T(AC), P2Y(AC), P2Y(12)R, P2Y(ADP), P2Y(cyc)
• UniprotQ9H244
• Concentration 0.6mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C/1 year

• Predicted MW: 39kd
  ELISA: 1:1000-1:5000
  Western blotting: 1:500-1:2000
  Immunohistochemistry: 1:25-1:100

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelets aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Two transcript variants encoding the same isoform have been identified for this gene.

• Gel: 10+12% SDS-PAGE
  Lane1: 293T celllysate
  Lane2: Hela cell lysate
  Lysates: 40ug per lane
  Primary antibody: 1/400 dilution
  Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/5000 dilution
  Exposure time: 30 seconds
  
• The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 31255 (P2RY12 Antibody) at dilution 1/25, on the right is treated with the synthetic peptide. (Original magnification: ×200)

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting