• Product NamePRDX1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• ApplicationsELISA WB IHC
• Species ReactivityHu Ms Rt
• SpecificityThe antibody detects endogenous level of total PRDX1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide peptide corresponding to a region derived from 103-115 amino acids of human peroxiredoxin 1
• Target NamePRDX1
• Alternative Names    peroxiredoxin 1, PAG, PAGA, PAGB, PRX1, PRXI, MSP23, NKEFA, TDPX2, NKEF-A
• Accession No. Swiss-Prot:Q06830
  Gene ID:5052;
• UniprotQ06830
• Gene ID5052;
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C/1 year

• Predicted MW: 22kd
  ELISA: 1:1000-1:2000
  Western blotting: 1:200-1:1000
  Immunohistochemistry: 1:25-1:100

This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Four transcript variants encoding the same protein have been identified for this gene.?

• Gel: 12% SDS-PAGE
  Lane1-9: Mouse liver tissue, Mouse kidney tissue, Human fetal brain tissue, NIH/3T3 cell, RAW264.7 cell, 293T cell, K562 cell, Jurkat cell and Hela cell lysate
  Lysates: 40ug per lane
  Primary antibody: 1/400 dilution
  Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/5000 dilution
  Exposure time: 50 seconds
  
• The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using 31263 (PRDX1 Antibody) at dilution 1/20, on the right is treated with the synthetic peptide.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting