• Product NameTRIM63 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• ApplicationsHuman, Mouse
• Species ReactivityHu
• SpecificityThe antibody detects endogenous level of total TRIM63 protein.
• Immunogen TypePeptide-KLH
• Immunogen DescriptionSynthetic peptide peptide corresponding to a region derived from 2-14 amino acids of human tripartite motif containing 63, E3 ubiquitin protein ligase
• Target NameTRIM63
• Alternative Names    tripartite motif containing 63, E3 ubiquitin protein ligase, IRF, SMRZ, MURF1, MURF2, RNF28
• Accession No. Swiss-Prot:Q969Q1
  Gene ID:84676;
• UniprotQ969Q1
• Gene ID84676;
• Concentration 1.2mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C/1 year

• Predicted MW: 40kd
  ELISA: 1:2000-1:10000
  Western blotting: 1:1000-1:5000
  Immunohistochemistry: 1:25-1:100

This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase.

• Gel: 10% SDS-PAGE
  Lysate: 40µg Human fetal muscle tissue lysate
  Primary antibody: 1/1050 dilution
  Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/5000 dilution
  Exposure time: 50 seconds
• The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 31279 (TRIM63 Antibody) at dilution 1/60, on the right is treated with the synthetic peptide.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting