• Product NameDRP-2 (Phospho-Thr514) Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
• ApplicationsWB
• Species ReactivityHu Ms Rt
• SpecificityThe antibody detects endogenous level of DRP-2 only when phosphorylated at Threonine 514.
• Immunogen TypePeptide-KLH
• Immunogen DescriptionPeptide sequence around phosphorylation site of Threonine 514 (K-V-T(p)-P-A) derived from Human DRP-2.
• Target NameDRP-2
• ModificationPhospho
• Alternative Names    DRP2, N2A3, CRMP2, DRP-2, ULIP2
• Accession No. Swiss-Prot#: Q16555;
  NCBI Gene#: 1808;
  NCBI Protein#: NP_001184222.1
• UniprotQ16555
• Gene ID1808;
• SDS-PAGE MW 65-70kd
• Concentration 1.0mg/ml
• Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C/1 year

• Predicted MW: 65-70kd
  Western blotting: 1:500~1:1000

Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton By similarity. Plays a role in neuron projection morphogenesis.

• Western blot analysis of extracts from Mouse brain tissue using DRP-2 (Phospho-Thr514) Antibody #12055.The lane on the left is treated with the antigen-specific peptide.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting