• Product NameMAP4K4(Phospho-Ser629) Antibody FITC Conjugated
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationPurified by Protein A.
• ApplicationsIF
• Species ReactivityHu Ms Rt
• Immunogen DescriptionKLH conjugated synthetic phosphopeptide derived from human MAP4K4 around the phosphorylation site of Ser629
• ConjugatesFITC
• Excitation Emission494nm 518nm
• Target NameMAP4K4 Ser629
• Alternative Names    MAP4K4phospho S629; Hepatocyte progenitor kinase like germinal center kinase like kinase; HGK; HPK GCK like kinase; HPK GCK like kinase HGK; KIAA0687; MAPK ERK kinase kinase kinase 4; MEK kinase kinase 4; MEKKK 4; MEKKK4; Mitogen activated protein kinase kinase kinase kinase 4; Nck interacting kinas
• Accession No.
  NCBI Gene ID9448
• UniprotO95819
• Gene ID9448;
• Concentration 1mg ml
• Formulation 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
• Storage Shipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.

• IF=1:50-200

MAP4K4 (Mitogen-activated protein kinase kinase kinase kinase 4) belongs to the serine threonine protein kinase family and specifically activates MAPK8 JNK. It may play a role in the response to environmental stress and is thought to function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF alpha signaling pathway. It interacts with the SH3 domain of the adapter protein Nck. MAP4K4-dependent signaling inhibits PPARG responsive gene expression, adipogenesis, and insulin stimulated glucose transport.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting