• Product NameAIM2 Antibody FITC Conjugated
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationPurified by Protein A.
• ApplicationsFlow-Cyt IF
• Species ReactivityHu Ms Rt
• Immunogen DescriptionKLH conjugated synthetic peptide aa 250-300 354 derived from mouse AIM2
• ConjugatesFITC
• Excitation Emission494nm 518nm
• Target NameAIM2
• Alternative Names    Gm1313; Ifi210; Interferon-inducible protein AIM2; Interferon-inducible protein 210; Ifi-210; Interferon-inducible protein p210; Aim2
• Accession No. Swiss-Prot#Q91VJ1
  NCBI Gene ID383619
• UniprotQ91VJ1
• Gene ID383619;
• Cell Localization Cytoplasm, Nucleus
• Concentration 1mg ml
• Formulation 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
• Storage Shipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.

• Flow-Cyt=1:50-200 IF=1:50-200

Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting