• Product NameGADD153 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationImmunogen affinity purified
• ApplicationsWB IHC IF/ICC
• Species ReactivityHu Ms Rt
• SpecificityGADD153 Antibody detects endogenous levels of GADD153
• Immunogen TypePeptide
• Immunogen DescriptionA synthesized peptide derived from human GADD153
• Target NameGADD153
• Alternative Names    C/EBP-homologous protein, DDIT3, DNA-damage inducible transcript 3, GADD153, Growth arrest and DNA-damage-inducible protein GADD153 Molecular weight: 19174.8 chop
• Accession No. Swiss-Prot#: P35638
• UniprotP35638
• Gene ID1649;
• SDS-PAGE MW 26KD
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20°C/1 year

• WB: 1:500-1:2000

  IHC: 1:50-1:200
  IF/ICC: 1:100-1:500

 CHOP a transcriptional-regulatory protein of the bZIP family. Inhibits the DNA-binding activity of C/EBP and LAP by forming heterodimers that cannot bind DNA. May play an important role in melanoma progression. CK2-mediated phosphorylation inhibits its transcriptional activity. Up-regulates IL-6 transcription by trapping negative regulating NF-IL6 isoform.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting