• Product NamePP1C Monoclonal Antibody
• Host SpeciesMouse
• ClonalityMonoclonal
• Clone No.2F2-A3-H10
• IsotypeIgG2b
• PurificationAffinity purified
• ApplicationsWB
• Species ReactivityHu
• SpecificityThis antibody detects endogenous levels of PPP1CC and does not cross-react with related proteins.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionPurified recombinant human PPP1CC protein fragments expressed in E.coli.
• Target NamePP1C
• Alternative Names    EC 3.1.3.16; PP 1G; PP-1G; PP1G; PP1G_HUMAN; PP1gamma; PPP 1G; PPP1CC; PPP1CC protein; PPP1G; Protein phosphatase 1 catalytic subunit gamma isoform; Protein phosphatase 1C catalytic subunit; Protein phosphatase 1C subunit
• Accession No. Uniprot: P36873

  Gene ID: 5501

• UniprotP36873
• Gene ID5501;
• SDS-PAGE MW 38kd
• Formulation Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine(pH 7.4,150 mM NaCl)with 0.2% sodium azide,0.1mg/mlBSA and 50% glycerol.
• Storage store at -20˚C

•  Western blotting: 1:500

 Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets.Protein phosphatase 1(PP1)is essential for cell division,and participates in the regulation of glycogen metabolism,muscle contractility and protein synthesis.Dephosphorylates RPS6KB1.Involved in regulation of ionic conductances and long-term synaptic plasticity.May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca2+/calmodulin dependent protein kinase II.Component of the PTW/PP1 phosphatase complex,which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.

• Western blot detection of PPP1CC antibody in Hela,293T and Jurkat cell lysates using PPP1CC antibody (1:500 diluted).Predicted band size:38KDa.Observed band size:38KDa.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting